These results highlighted the role of κ-CGN in alleviating diet-induced adiposity by promoting energy expenditure and suppressing the bioavailability of ingested lipids.

Moreover, κ-CGN in high-fat diets inhibited lipid digestion and absorption, being associated with the decrease in lipid accumulation and improved serum lipid profile. The sirtuin1-mediated improvement of lipid metabolism was negatively associated with the levels of bile acids, especially for deoxycholic acid, 3β-cholic acid, glycodeoxycholic acid and glycolithocholic acid. Download scientific diagram Representative structure of lipids. Supplement of κ-CGN in high-fat diets significantly upregulated the genes and protein expression of Sirtuin1, which was accompanied by the increased gene expression of downstream fatty acids oxidation ( Cpt1a and Acadl). The κ-CGN supplement significantly suppressed the increase in body weight by 6.79 g on an average. The current study investigated the effect of κ-CGN in pork-based diets on the lipid metabolism of male C57BL/6J mice. However, its impact on the host metabolism is less revealed. Online ahead of print.Kappa-carrageenan (κ-CGN) is widely used in the meat industry. When the structure is disordered, the stratum corneum is considered to be loosely organized, whereas with a well-ordered structure, it is considered to be well organized. *1 Term for the structure of intercellular lipids. Shiseido has promoted the development of cleansing products that cleanse without removing the essential moisture necessary for healthy skin, and going forward, we will strive to develop unprecedented high value-added cleansing products with the application of this technology. Furthermore, the unique ingredient remains in the stratum corneum after being applied to the skin and washed off. With this method, we have confirmed that a uniquely developed ingredient, EPDMEs, improves the structural ordering*1 of intercellular lipids and maintains barrier function*2. Shiseido Company, Limited (“Shiseido”) and the Research Institute for Electronic Science at Hokkaido University have succeeded in jointly establishing a new method for evaluating intercellular lipids in the stratum corneum, which are strongly related to the barrier function of the skin.

Structure of lipids download